The aim of this issue is to provide an overview of current research into frame semantics and construction grammar, and to stimulate the dialogue between these frameworks and the notion of framing in other linguistic traditions. Using Fillmore’s frame semantics as a common source of inspiration, the volume examines a spectrum of semantic issues, from a theoretical and more applied perspective. Among the topics that are addressed are the relation between frames and other (cognitive) grammatical models, ontologies and discourse analysis, as well as the methodological difference between top-down and bottom-up approaches. The eight articles on grammatical, lexical and discursive forms cover issues as diverse as political discourse in Belgium, France and the USA, Czech function words, English communication verbs, modality and the relation between instrumentals and causality in LSP. Researchers from theoretical and applied linguistics interested in the form/meaning interface and authentic discourse data may appreciate this work as a valuable resource for further reflection on the relation between grammar and the lexicon, frames and ontology.